Breast cancer diagnosis does not impact response to ovarian stimulation, according to study

Researchers aimed at finding out if a breast cancer diagnosis impacts ovarian function in the setting of fertility preservation.

This cohort analysis included 589 patients undergoing ovarian stimulation for fertility preservation between 2009 and 2015. Women with a recent breast cancer diagnosis and women desiring elective fertility preservation underwent ovarian stimulation with an antagonist protocol.

According to the findings of the study, published in Human Reproduction “ovarian reserve and ovarian stimulation outcomes are similar in patients with a new diagnosis of breast cancer and patients undergoing elective fertility preservation”

“A breast cancer diagnosis does not impact gonadal function as measured by AFC or ovarian stimulation outcomes. Breast cancer patients should be counseled that their response to ovarian stimulation for fertility preservation is similar to that of patients undergoing elective oocyte cryopreservation”, according to the researchers.

In this study, researchers admitted two limitations: they used data from a single center and there was a lack of subsequent embryo and pregnancy data.

Previous studies had reported conflicting outcomes for cancer patients undergoing ovarian stimulation for fertility preservation.

Read more: https://academic.oup.com/humrep/article-abstract/doi/10.1093/humrep/dew355/2952938/Response-to-ovarian-stimulation-is-not-impacted-by?redirectedFrom=fulltext

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breast cancer ovarian stimulation